RotaChrom Blog Highlights
Selected articles from our legacy blog. Click any card to read the full post.
When the Matrix Is the Main Challenge: CPC for the Enrichment of Bioactives from Insect Larvae
Natural product purification rarely starts from a clean sample. In many cases, the real challenge is not only the target compound itself, but the matrix surrounding it. Lipids, pigments, degradation products, structurally related compounds and other co-extracted materials can…
szeptember 30, 2026 · Education
When Lab-Scale Chromatography Stops Working: The Hidden Challenges of Industrial Scale-Up
A purification process that works well at laboratory scale does not always translate directly to pilot or industrial production. This is particularly relevant for traditional packed-bed solid-phase chromatography, including silica-based preparative chromatography, where…
szeptember 24, 2026 · Education
RotaChrom Introduces Its Next-Generation In-House Software Platform for Centrifugal Partition Chromatography Systems
For RotaChrom, innovation does not stop with the equipment. RotaChrom has developed a new, fully in-house software platform designed to provide a unified digital environment across its CPC systems.As a leading innovator in centrifugal partition chromatography (CPC) technology…
szeptember 7, 2026
How Does RotaChrom Support CPC Process Engineering and System Integration?
Once a purification method has been developed, translating laboratory results into a production-ready process becomes the next challenge. RotaChrom's CPC process engineering services support the development of scalable industrial workflows. This includes:- User Requirements…
szeptember 1, 2026
What Services Can RotaChrom Offer for CPC Purification?
Developing a reliable purification process requires more than selecting a chromatography technology.RotaChrom provides CPC purification services covering the complete development journey from initial feasibility studies and CPC method development to process engineering…
augusztus 27, 2026
Choosing Green Chemistry in Chromatography
Sustainability is becoming an increasingly important consideration in pharmaceutical, biotechnology and chemical manufacturing. As purification processes move from laboratory method development to industrial process development, solvent consumption, waste generation, product…
augusztus 12, 2026
How to Reduce Solvent Consumption in Preparative Chromatography
Reducing solvent consumption in preparative chromatography is becoming a top priority. Rising solvent costs, stricter environmental regulations and sustainability goals are driving manufacturers to rethink how purification processes are designed.Organic solvents represent a…
augusztus 6, 2026
Scale-Up or Scale-Out?
As purification demands grow from laboratory development toward pilot and industrial production, one of the first questions process engineers face is simple:
július 30, 2026
Understanding CPC Operation Modes: Ascending, Descending and Multiple Dual-Mode (MDM)
Choosing the right operating mode is one of the most important decisions in Centrifugal Partition Chromatography (CPC) method development. Solvent-system selection and partition coefficients (Kd) determine whether a separation is chemically feasible. However, the operating mode…
július 27, 2026
CPC Simulator: Accelerating Centrifugal Partition Chromatography Method Development
Developing a successful Centrifugal Partition Chromatography (CPC) method often requires extensive solvent screening, multiple laboratory experiments and significant development time. While CPC is widely recognized for its scalability and high product recovery, CPC method…
július 14, 2026
How to run a feasibility study on CPC
Feasibility study or FST, is the first practical steps in CPC (Centrifugal Partition Chromatography) method development. It enables the early evaluation of whether a target compound, matrix or purification objective can be efficiently addressed by CPC before moving toward full…
július 2, 2026
From Solvent Selection to Robust CPC Method Development
Successful CPC purification is the result of a carefully developed method rather than a single experimental decision. After a promising biphasic solvent system has been identified, the next step is to understand how the target compound and its impurities behave within that…
június 24, 2026
From extraction to purification: understanding liquid-liquid extraction (LLE), liquid-liquid chromatography (LLC) and centrifugal partition chromatography (CPC)
The purpose of extraction is simple: transfer a target compound from a complex raw material into a more manageable phase where it can be concentrated and further processed. However, a common misconception is that extraction automatically produces a pure product.In real process…
június 12, 2026
Why downstream purification and scale-up are slowing pharmaceutical innovation
The pharmaceutical industry has made extraordinary advances in research and molecular innovation, drug discovery, precision medicine, biologics, nucleic acid therapeutics and personalized therapies. However, from small molecule drugs to advanced biologics and…
június 3, 2026
Reflecting on GA 2025: Insights from the International Congress on Natural Products in Naples
Last week, our team had the privilege of attending the 73rd International Congress and Annual Meeting of the Society for Medicinal Plant and Natural Product Research (GA), jointly organized with the Italian Society of Phytochemistry (SIF) in Naples from 31 August to 3 September…
szeptember 9, 2025
RotaChrom and Inkarp Announce Strategic Partnership to Advance Chromatographic Purification in India
RotaChrom Technologies is proud to announce a new strategic partnership with Inkarp, one of India's most trusted providers of laboratory solutions. This collaboration is set to introduce RotaChrom’s full suite of centrifugal partition chromatography (CPC) platforms to the…
július 30, 2025 · News
Red Mesa Sets the Standard in Cannabinoid Purification with Industrial-Scale CPC
In a rapidly evolving regulatory environment where traditional hemp refining methods face increasing scrutiny, centrifugal partition chromatography (CPC) is emerging as the gold standard for high-purity cannabinoid isolation. Among the pioneers embracing this transformative…
július 9, 2025
Chemspec 2025 – A Recap
Chemspec Europe 2025: RotaChrom Showcases Isomer Purification and Expands Industry Connections
június 16, 2025 · Conferences, Exhibitions, News
Addressing pH Issues in Chromatography: From Solid-Phase to Liquid-Liquid Separations
Selecting the appropriate stationary and mobile phases is a critical step in chromatographic method development. The primary objective is to achieve effective separations, characterized by sharp, symmetrical, and well-resolved peaks. However, challenges can arise when the…
május 15, 2025 · Education, News
Chemspec 2025
If you work in chemical synthesis, pharmaceutical manufacturing, or high-performance purification, you won’t want to miss Chemspec 2025 this year. This international exhibition for fine and specialty chemicals is taking place in Koelnmesse from June 04–05, and RotaChrom…
május 15, 2025 · Conferences, Education, Exhibitions, News
RotaChrom at Flow Chemistry Europe 2025: Exploring Innovation Through CPC Technology
Flow Chemistry Europe 2025 (FCE-25), held in the vibrant city of Málaga, Spain, provided an exceptional platform for scientific exchange and technological inspiration. RotaChrom Technologies was proud to be represented by our Business Development Specialist, Réka Szabó, who not…
április 16, 2025 · Events, News
SZTE’s Award-Winning Innovation: A Natural Breakthrough in Obesity Prevention
Obesity and metabolic disorders have become major public health challenges worldwide, increasing the risk of diabetes, hypertension, and cardiovascular diseases. In a groundbreaking research project conducted by the University of Szeged (SZTE), scientists discovered a promising…
február 4, 2025 · Education, News, Studies
Innovations in Chiral Purification: Exploring Techniques and Future Potential
Chiral separation represents one of the most intricate challenges in both analytical and preparative chemistry. As pharmaceutical applications increasingly demand enantiomerically pure compounds, chromatography has emerged as a vital tool for resolving stereoisomers. From gas…
január 31, 2025 · Download, Education, News
Optimizing Chromane Epoxide Separation for Nebivolol Synthesis with Chromatography
Chromatography remains at the forefront of isomer separation, crucial for pharmaceuticals where purity and stereochemistry directly impact efficacy and safety. Isomers, particularly stereoisomers, are pivotal in drug development as they often exhibit distinct biological…
január 24, 2025 · Download, Education, News
Sustainable Purification of Amberketal: Centrifugal Partition Chromatography for Fragrance Industry Applications (Isomerism Part 3)
Amberketal, a synthetic equivalent of the highly valued natural ambergris, has gained prominence in the fragrance industry due to its rich woody aroma and its potential for sustainable production. Derived from the bark of the western white pine (Pinus monticola), amberketal is…
november 18, 2024 · Download, Education, News
Unraveling the Separation and Enrichment of Vitamin E Isomers: A Focus on Tocotrienols (Isomerism Part 2)
Vitamin E is an essential lipid-soluble antioxidant known for its protective effects against oxidative damage, potentially reducing the risk of certain diseases. Among its compounds, tocopherols and tocotrienols are the primary forms, each existing as different constitutional…
november 14, 2024 · Download, Education, News
The Science and Strategy Behind Isomer Separation: Advancements in Chromatography for Precision Purification (Isomerism Part 1)
In fields like pharmaceuticals, biotechnology, and petrochemicals, the separation of isomers is crucial due to their unique properties and potential applications. Isomers—molecules with the same molecular formula but different structures—can exhibit vastly different physical…
november 7, 2024 · Download, Education, News
Leveraging CPC Chromatography for Versatile Analytical and Preparative Applications
Centrifugal Partition Chromatography (CPC) has emerged as a versatile and effective technique for addressing a wide range of chromatographic challenges. Its unique approach of using liquid-liquid partitioning enables its application in both analytical and preparative scales…
szeptember 5, 2024 · Education, News
Revolutionizing Complex Mixture Purification with Industrial-Scale Centrifugal Partition Chromatography (CPC)
The manufacturing and purification of small molecule Active Pharmaceutical Ingredients (APIs) is a multifaceted process requiring specialized facilities, regulatory expertise, and scientific acumen. To navigate this complex landscape, pharmaceutical innovators often collaborate…
augusztus 23, 2024 · Education, News
Centrifugal Partition Chromatography (CPC): Greener and More Sustainable
Traditional chromatography methods, particularly those utilizing solid supports like silica gel columns, require large volumes of solvents for elution. This high solvent consumption poses significant environmental and economic concerns, especially when hazardous organic…
augusztus 13, 2024 · News
The Differences Between CPC and Multicolumn Countercurrent Solvent Gradient Purification (MCSGP)
MCSGP offers several benefits compared to traditional chromatographic methods. However, it is still outperformed by a competitive technology, centrifugal partition chromatography (CPC).This novel system eliminates the need for a solid stationary phase, such as silica gel, to…
augusztus 8, 2024 · Education, News
The pCPC: RotaChrom’s Tailor-Made Purification System
The pCPC (Preparative Centrifugal Partition Chromatography) is a specialized system developed by RotaChrom designed to handle a variety of purification tasks. It combines two major components: the iCPC, RotaChrom’s industrial-scale Centrifugal Partition Chromatography device…
július 29, 2024 · Education, News
Centrifugal Partition Chromatography and Simulated Moving Bed Compared
Continuous manufacturing, also known as flow manufacturing, is a crucial approach in industrial production that involves the seamless and uninterrupted creation of products, eliminating stops or pauses between successive batches. Unlike batch manufacturing, which involves…
július 18, 2024 · Education, News
The n-Hexane/Ethyl Acetate/Methanol/Water (HEMWat) Solvent System in Centrifugal Partition Chromatography
Centrifugal partition chromatography (CPC) relies heavily on the choice of solvent systems to achieve effective separation of complex mixtures. One such solvent system that has proven to be highly effective is the n-hexane/ethyl acetate/methanol/water system. (HEMWat) This…
június 7, 2024 · Education, News
Centrifugal Partition Chromatography (CPC): A Sustainable Approach for Complex Mixture Separation
Chromatography remains a cornerstone in scientific techniques for effectively separating and purifying complex mixtures. Within this realm, Centrifugal Partition Chromatography (CPC) stands out due to its utilization of liquid-liquid partitioning for separation. A key element…
május 20, 2024 · Education, News
Enhancing API Manufacturing with Contract Development and Manufacturing Organizations (CDMOs) and Industrial-Scale Centrifugal Partition Chromatography (CPC)
The manufacturing of small molecule Active Pharmaceutical Ingredients (APIs) is a multifaceted process requiring specialized facilities, regulatory expertise, and scientific acumen. To navigate this complex landscape, pharmaceutical innovators often collaborate with Contract…
május 15, 2024 · Education, News
Optimizing Solvent Consumption for Your Chromatographic Solution
Centrifugal Partition Chromatography (CPC) is emerging as a sustainable alternative to traditional chromatography methods, addressing environmental concerns effectively. Let’s explore why traditional chromatography is considered unsustainable and how CPC offers a greener…
május 10, 2024 · Education, News
The Principles and Advantages of Centrifugal Partition Chromatography (CPC)
Centrifugal Partition Chromatography (CPC) is rapidly gaining recognition as a highly efficient and effective preparative chromatographic technique. Its unique approach, utilizing two immiscible liquid solvent systems as both stationary and mobile phases, sets it apart from…
május 5, 2024 · Education, News
Centrifugal Partition Chromatography (CPC): A Sustainable Alternative to Traditional Chromatography Methods
Chromatography, a cornerstone technique in chemical analysis and separation, has long been dominated by methods that, despite their effectiveness, pose significant environmental challenges. Traditional chromatography often relies on solid supports like silica gel columns…
május 1, 2024 · Education, News
RotaChrom’s Continuous CPC Platform: Revolutionizing Chromatographic Techniques
In the domain of chromatography, RotaChrom’s Continuous Centrifugal Partition Chromatography (Continuous CPC) platform stands as a beacon of innovation, heralding a new era in separation and purification processes. This article delves into the intricacies of this revolutionary…
április 20, 2024 · News
The Sustainable Promise of CPC
Preparative-scale liquid chromatography has long been a stalwart in the chemical industry for purification processes. However, the environmental toll of substantial solvent consumption and solid waste from spent silica gel packing has prompted a shift towards sustainable…
április 11, 2024 · Education, News
Analytical and Preparative Chromatography: A Comparative Exploration
Chromatography, a fundamental technique in chemical analysis, is broadly categorized into two types: analytical and preparative. Each serves distinct purposes based on scale and separation objectives. In this article, we explore the characteristics and applications of both…
április 5, 2024 · Education, News
The Rise of Centrifugal Partition Chromatography (CPC): A Revolutionary Technique
Centrifugal Partition Chromatography (CPC) has rapidly become a highly effective and efficient preparative chromatographic technique, gaining traction among scientists, researchers, and laboratory technicians alike. By utilizing two immiscible liquid solvent systems as both…
április 3, 2024 · Education, News
Conclusion
In the realm of bioprocessing, the quest for efficient and scalable purification methods remains a constant challenge. This study delves into the application of centrifugal partition chromatography (CPC) for isolating recombinant human albumin (rHA) from fermentation broth…
március 19, 2024 · Education, News
The Pursuit of Purity: Elevating Anastrozole Production with CPC
In the realm of pharmaceuticals, precision and purity are paramount. Anastrozole, a potent aromatase inhibitor, holds immense significance in the treatment of hormone receptor-positive breast cancer. However, achieving the requisite purity levels mandated by stringent…
március 13, 2024 · Download, Education, News
A Deep Dive into Centrifugal Partition Chromatography (CPC)
Centrifugal Partition Chromatography (CPC) represents a revolutionary advancement in the field of chromatographic techniques, combining the principles of traditional liquid-liquid chromatography (LLC) with the enhanced force of centrifugation. Unlike conventional chromatography…
március 12, 2024 · News
Revolutionizing API Manufacturing: The Role of CDMOs and RotaChrom's CPC Technology
The manufacturing of small molecule Active Pharmaceutical Ingredients (APIs) is a complex and highly regulated process, demanding specialized facilities, regulatory expertise, and scientific acumen. In navigating this intricate landscape, pharmaceutical innovators often rely on…
március 9, 2024 · Education, News
Revolutionizing CBD Production: THC Removal Using rCPC Purification
The burgeoning market for cannabidiol (CBD) products continues to thrive, fueled by increasing consumer demand for natural remedies and wellness solutions. However, ensuring the purity and legality of CBD extracts remains a critical concern for manufacturers. In this study, we…
március 7, 2024 · Education, News
Liquid-Liquid Chromatography's Role in the Nonlinear Range
Liquid-liquid chromatography (LLC) stands out as a potent technique in analytical chemistry, enabling the separation and purification of compounds based on their distribution between two immiscible phases. While much attention has been focused on the linear range of the…
február 20, 2024 · News
Optimizing Solvent Consumption For Your Chromatographic Solution
Centrifugal Partition Chromatography (CPC) is emerging as a sustainable alternative to traditional chromatography methods, offering solutions to address environmental concerns. Let's delve into the reasons why traditional chromatography is deemed unsustainable and how CPC…
február 11, 2024 · News
Unveiling the Power of Centrifugal Partition Chromatography
Chromatography, a cornerstone of scientific endeavors, finds its pinnacle in Centrifugal Partition Chromatography (CPC), a liquid-liquid partitioning technique revolutionizing separation and purification. At the heart of CPC lies the partition coefficient (Kd), dictating the…
február 7, 2024 · News
Transforming Chromatography: Exploring RotaChrom's Continuous CPC Platform
In the domain of chromatography, RotaChrom's Continuous Centrifugal Partition Chromatography (Continuous CPC) platform stands as a beacon of innovation, heralding a new era in separation and purification processes. This article delves into the intricacies of this revolutionary…
február 3, 2024 · News
Centrifugal Partition Chromatography (CPC): An Essential Tool in Scientific Exploration
Centrifugal partition chromatography (CPC) has emerged as a highly effective and efficient preparative chromatographic technique, gaining popularity among scientists, researchers, and laboratory technicians. Utilizing two immiscible liquid solvent systems as both stationary and…
január 25, 2024 · Education, News
CPC Chromatography: A Versatile Solution for Analytical and Preparative Scale Purifications
CPC Chromatography proves highly effective in addressing chromatographic challenges, offering versatile applications on both analytical and preparative scales. The distinct objectives of each scale highlight the adaptability of CPC in overcoming challenges associated with…
január 20, 2024 · Education, News
Here's Why You Should Use Chromatography In Your Purification
Centrifugal Partition Chromatography (CPC) represents a revolutionary chromatographic technique that integrates traditional liquid-liquid chromatography (LLC) with the force of centrifugation. Unlike conventional chromatography, CPC employs interconnected cells in lieu of…
január 15, 2024 · Education, News
Centrifugal Partition Chromatography (CPC): A Sustainable Paradigm Shift
Traditional chromatography methods face sustainability challenges, primarily driven by high solvent consumption, solid waste generation, and limited solvent choices. CPC emerges as a greener alternative, revolutionizing chromatography by eliminating the need for solid supports…
január 15, 2024 · News
Evolution of Cannabis Classification: A Modern Perspective
For millennia, cannabis has served medicinal purposes. In the 18th century, the classification of cannabis into Indica, Sativa, and sometimes Ruderalis emerged for commercial use, gaining popularity among recreational users. However, contemporary scientists challenge this…
január 10, 2024 · Education, News
Navigating the Chromatography Journey: A Comprehensive Guide to Process Steps
Chromatography, a cornerstone technique in separation science, holds immense significance across various industries. Understanding the intricacies of the chromatography process is essential for researchers, scientists, and industry professionals seeking to harness its…
december 19, 2023 · Education, News
Revolutionizing API Manufacturing: RotaChrom's Liquid-Liquid Chromatography Approach
The manufacturing of small molecule Active Pharmaceutical Ingredients (APIs) is a multifaceted process, demanding specialized facilities, regulatory acumen, and scientific expertise. To navigate this complex landscape, pharmaceutical innovators often turn to Contract…
december 17, 2023 · Education, News
Unveiling the World of Chirality: Exploring Chiral Molecules and Chromatography
Chirality, the property of molecules that possess non-superimposable mirror images, plays a crucial role in various fields, from pharmaceuticals to fragrances. This article delves into the realm of chirality, exploring its significance and the specialized technique of chiral…
december 10, 2023 · Education, News
Mastering the Art of Chromatographic Separation: The Balance of Yield, Purity, and Throughput
Chromatographic techniques play a pivotal role in separating and purifying components within a mixture, presenting a key challenge for chromatographers. Striking a balance between yield, purity, and throughput is essential for successful purification. In this article, we…
december 5, 2023 · Education, News
Unveiling the Power of CPC in Preparative Chromatography
Centrifugal partition chromatography (CPC) has emerged as a highly effective and efficient preparative chromatographic technique, gaining significant popularity among scientists, researchers, and laboratory technicians. Utilizing two immiscible liquid solvent systems as both…
december 1, 2023 · Education, News
Pioneering Sustainability in Chemical Purification: The Green Revolution of Centrifugal Partition Chromatography
Preparative-scale liquid chromatography has long been a stalwart in the chemical industry for purification processes. However, the environmental toll of substantial solvent consumption and solid waste from spent silica gel packing has prompted a shift towards sustainable…
november 16, 2023 · Education, News
Unraveling the Fundamentals of Chromatography and Its Diverse Methods
Chromatographic separation, a cornerstone in analytical science, involves the strategic division of mixtures into stationary and mobile phases. As the mobile phase traverses in a defined direction under forces like gravity or pressure, it carries sample components along…
november 13, 2023 · Education, News
Exploring Chromatographic Methods: Analytical vs. Preparative Chromatography
Chromatography, a fundamental technique in chemical analysis, is broadly categorized into two types: analytical and preparative. Each serves distinct purposes based on scale and separation objectives. In this article, we explore the characteristics and applications of both…
november 10, 2023 · Education, News
Revolutionizing Chromatography: RotaChrom's Continuous CPC Platform
In the realm of chromatography, RotaChrom's Continuous Centrifugal Partition Chromatography (Continuous CPC) platform represents a groundbreaking leap into the future. This revolutionary technology goes beyond traditional batch processes, introducing a continuous and highly…
november 5, 2023 · News
RotaChrom x HEPA: Building International Connections
RotaChrom Technologies was invited to a prestigious event organized by the Budapest HEPA Hungarian Export Promotion Agency, to take part in an event for building connections and showcasing the backgrounds of the invited. Among the invitees were RotaChrom's Chief Executive…
október 18, 2023 · Events, News
Understanding Chromatography: A Tool for Complex Mixture Separation and Purification
Chromatography stands as a widely embraced technique in the field of science for effectively separating and purifying complex mixtures. Within this realm, Centrifugal Partition Chromatography (CPC) stands out as a unique chromatographic approach, utilizing liquid-liquid…
október 15, 2023 · Education, News
Understanding Chromatography: Basics of CPC
Centrifugal Partition Chromatography (CPC) has emerged as an incredibly efficient preparative chromatographic technique, steadily gaining popularity within the scientific community. This innovative method employs two immiscible liquid solvent systems, serving as both the…
október 10, 2023 · Education, News
Understanding Chromatography: Analytical and Preparative Separations
Chromatographic methodologies can be categorized into two main types: analytical and preparative, based on the scale and objective of the separation process. Analytical methods are focused on obtaining qualitative and quantitative data about the sample under investigation.On…
október 5, 2023 · Education, News
Understanding Chromatography: Types and Methods
Chromatographic separation involves dividing a mixture into a stationary phase and a mobile phase. The mobile phase moves in a particular direction, propelled by forces like gravity or pressure differences, carrying the sample components with it.Components that strongly…
október 2, 2023 · Download, Education, News
An Introduction to Continuous Purification
Centrifugal Partition Chromatography (CPC) has taken a leap into the future with RotaChrom's revolutionary Continuous CPC platform. Unlike traditional batch processes, this innovative technology offers a continuous, uninterrupted, and highly efficient method for separation and…
szeptember 28, 2023 · Download, Education, News
Separation of Remdesivir Diastereomeres by Centrifugal Partition Chromatography
RotaChrom’s Lead Scientific Officer Arpad Konczol recently did a webinar presentation detailing continuous chromatography, and how you can apply said technology for maximum purification benefits.
szeptember 25, 2023 · Education, News, Webinars
Getting the Most Out of Your Chromatographic Solvent System
Centrifugal Partition Chromatography (CPC) is indeed a promising alternative to traditional chromatography methods, particularly in addressing sustainability concerns. Here's an overview of why traditional chromatography is seen as unsustainable and how CPC offers a greener…
szeptember 10, 2023 · Download, Education, News
A Guide to Solvent Choice in Chromatographic Systems
Preparative-scale liquid chromatography, while widely used in the chemical industry for purification, encounters sustainability challenges due to substantial solvent consumption and the generation of solid waste from spent silica gel packing. This has spurred interest in…
szeptember 5, 2023 · News
ILMAC 2023: Meet Our Team and Learn About Chromatography
Our lovely team is looking forward to meet you at ILMAC 2023! If you'd like to shake hands with them and talk chromatography, visit Messe Basel between September 23 and 28 at Hall 1.0, booth E186. Don't forget to look for our mountaintop booth design and the rCPC device.There…
szeptember 1, 2023 · Conferences, Events, Exhibitions, News
Modes of Chromatography, Explained
Centrifugal Partition Chromatography (CPC) is a game-changer in the realm of chromatographic techniques, redefining the paradigm by discarding conventional columns and adopting interconnected cells. These cells, resembling columns, are linked in a series through ducts connected…
augusztus 30, 2023 · Download, Education, News
Analytical and Preparative Chromatography, Explained
In chromatography, the pursuit of isolating and refining individual components within a mixture is a fundamental objective. However, attaining pure compounds isn't always a straightforward venture. Chromatographers are faced with the challenge of striking a delicate balance…
augusztus 25, 2023 · Download, Education, News
Active Pharmaceutical Ingredients Manufacturing and CDMOs
The manufacturing of small molecule Active Pharmaceutical Ingredients (APIs) is a complex and highly regulated process that necessitates specialized facilities, regulatory expertise, chemistry proficiency, and effective supply chain management. To overcome these challenges…
augusztus 15, 2023 · Download, Education, News
Chiral Molecules and Chromatography
Chirality and chiral molecules hold immense significance across various domains of chemistry, notably in pharmaceuticals, fragrances, and food additives. They pervade nature and have gained substantial importance due to their exceptional attributes. Prominent instances of…
augusztus 10, 2023 · Download, Education, News
The Core Objectives of Chromatography
Centrifugal Partition Chromatography (CPC) stands as a groundbreaking chromatographic technique, marrying the principles of traditional liquid-liquid chromatography (LLC) with the formidable force of centrifugation. While grounded in the fundamental tenets of conventional…
augusztus 5, 2023 · Education, News
Uses of Medical Cannabis
People have been using cannabis as medicine for thousands of years. In the 18th century, they started categorizing cannabis plants into types like Indica, Sativa, and sometimes Ruderalis for commercial purposes. These distinctions became popular, especially among recreational…
július 25, 2023 · Download, Education, News
An Introduction to Medical Cannabis
The historical use of cannabis as a medicinal remedy dates back thousands of years. During the 18th century, the categorization of cannabis plants into Indica, Sativa, and sometimes Ruderalis (as a commercial variety) gained prominence. Despite their popularity among…
július 20, 2023 · Download, Education, News
Standardized Therapeutic Extracts and The Potential of Recovering Valuable Compounds from Extraction Residues (Natural Extracts Part 3)
The significance of medicinal plants and crops has remained a focal point throughout history. Their well-documented and recognized positive impacts on health predate the advent of modern medicine, and even today, they continue to coexist alongside contemporary treatments as a…
július 18, 2023 · Download, Education, News
Centrifugal Partition Chromatography for Natural Extract Purification (Natural Extracts Part 2)
In the realm of isolating natural products, counter-current chromatography, with a special emphasis on centrifugal partition chromatography (CPC), assumes a pivotal role. The intricate task of chromatographic separation of diverse chemical constituents within complex extracts…
július 12, 2023 · Download, Education, News
Unlock the Secrets to Natural Extract Purification (Natural Extracts Part 1)
Throughout history, medicinal plants and crops have held a special place in human health practices. Their documented and recognized positive effects on well-being predate modern medicine and continue to coexist with it, often serving as a preferred mode of treatment. Companies…
július 3, 2023 · Download, Education, News
Industrial-Scale API Production (Part 2)
The production of small molecule Active Pharmaceutical Ingredients (APIs) is a complex and intricate process that demands specialized facilities, regulatory expertise, chemistry know-how, and efficient supply chain management. To navigate these challenges successfully, numerous…
június 25, 2023 · Education, News
Industrial-Scale API Production (Part 1)
The production of small molecule Active Pharmaceutical Ingredients (APIs) is a complex and intricate process that demands specialized facilities, regulatory expertise, chemistry know-how, and efficient supply chain management. To navigate these challenges successfully, numerous…
június 21, 2023 · Education, News
What is the 'Partition Coefficient'?
Chromatography stands as a widely adopted technique for separating and purifying complex mixtures. Among these methods, Centrifugal Partition Chromatography (CPC) stands out as a unique approach, relying on liquid-liquid partitioning to achieve effective separation. A…
június 17, 2023 · Education, News
HPLC 2023 – International Symposium on High-Performance Liquid Phase Separations and Related Techniques
The International Symposium on High-Performance Liquid Phase Separations and Related Techniques, also known as HPLC 2023 takes place from 18-22 June. RotaChrom scientists Dora Rutterschmid, Zalan Kadar and David Laczko will be there with individual posters.If you'd like to…
június 15, 2023 · Conferences, Events, News
An Alternative in Solvents: Centrifugal Partition Chromatography
Despite its widespread use in the chemical industry, traditional preparative-scale liquid chromatography faces sustainability challenges due to its high solvent consumption and the generation of solid waste from spent silica gel packing. However, there is hope for a more…
június 10, 2023 · News
Eliminate Impurities with Chromatography: Purifying Mitragynine
Mitragynine (MTR), a prominent alkaloid found in Mitragyna speciosa leaf extract, plays a significant role in the botanical known as "kratom." This plant, belonging to the Rubiaceae family, has garnered extensive attention in recent years due to its remarkable biological…
május 25, 2023 · News
Start Your Chromatography Journey: Separation, Isolation and Remediation
Centrifugal Partition Chromatography (CPC) is an innovative chromatographic technique that combines the principles of liquid-liquid chromatography (LLC) with the power of centrifugal force. While CPC follows the basic principles of traditional chromatography, its unique…
május 22, 2023 · News
Streamlining Purification with CPC: Purification Modes
Centrifugal Partition Chromatography (CPC) revolutionizes traditional chromatographic techniques by replacing conventional chromatographic columns with interconnected cells. These cells, which act as columns, are linked in series through ducts that are connected to a large…
május 19, 2023 · News
A Study of Nonlinearity in Chromatography
Liquid-liquid chromatography (LLC) stands as a potent technique within the realm of analytical chemistry, offering the ability to separate and purify a mixture of compounds based on their varying distribution between two immiscible phases. In this method, a biphasic solvent…
május 8, 2023 · Education, News
The Secrets to Mastering Chiral Chromatography
Chirality pertains to the characteristic of certain molecules that cannot be superimposed onto their mirror images, and chirality in chromatography refers to this characteristic in chromatographic separation. These molecules are known as "chiral" and are commonly described as…
május 3, 2023 · Education, News
The Cost-Effective Alternative to Supercritical Fluid Chromatography
Supercritical Fluid Chromatography (SFC) offers a distinct set of advantages compared to other chromatographic techniques. Let's explore these benefits in more detail.One of the key advantages of SFC is its effectiveness in cases where a particular separation method remains…
április 20, 2023 · News
Unlocking the Secrets of CPC Chromatography
CPC Chromatography is a great solution to many chromatographic challenges, whether it is large-scale or small-scale. Chromatographic separation can be carried out on two distinct scales: analytical and preparative. On the analytical scale, the primary objective of the…
április 17, 2023 · News
RotaChrom at Chemspec 2023
Click here to book a meeting with our Chief Product Officer, Andras Gaspar. See you at Chemspec 2023!
április 11, 2023 · Conferences, Events, Exhibitions, News
What is Good Manufacturing Practice (GMP)?
Click here and download your brochure containing even more in-depth knowledge about cGMP compliance and learning how you can update your current purification setup for GMP.
április 10, 2023 · Education, News
RotaChrom at Korea Lab 2023
RotaChrom is visiting Korea Lab 2023! If you’d like to learn more about centrifugal partition chromatography (CPC) technology, or meet the scientific team of RotaChrom, make sure to visit the Kintex Korea International Exhibition Center in Goyang from April 18 to April 21.
április 5, 2023 · Conferences, Events, Exhibitions, News
Here Is Your Missing Allrounder for Purification: CPC – RotaChrom at Chemspec
Click here to book a meeting with our Chief Product Officer, Andras Gaspar. See you at Chemspec 2023!
március 20, 2023 · Conferences, News
The Big Three: Maximizing the Potential of Separation, Isolation and Remediation
Separation, isolation, and remediation play crucial roles in chromatography, and we will delve into the reasons why in this discussion. While Centrifugal Partition Chromatography (CPC) adheres to the conventional principles of chromatography, it distinguishes itself by…
március 19, 2023 · Education, News
The Secrets to Producing Active Pharmaceutical Ingredients
The manufacture of small molecule Active Pharmaceutical Ingredients (APIs) is a multifaceted process that demands specialized facilities, regulatory expertise, chemistry proficiency, and efficient supply chain management. In order to address these challenges, many…
március 18, 2023 · Education, News
Understanding the Partition Coefficient
Chromatography is a widely used technique for separating and purifying complex mixtures. Centrifugal Partition Chromatography (CPC) is a unique chromatographic method that utilizes liquid-liquid partitioning to achieve separation. An essential feature of CPC is that the…
március 14, 2023 · Education, News
Maximizing Chromatographic Efficiency: A Guide to Mastering Recovery, Throughput, and Purity
Separating and purifying individual components of a mixture is a primary application of chromatographic techniques. However, achieving pure compounds is not always a straightforward process. Chromatographers must balance throughput, recovery, and purity, prioritizing the most…
március 2, 2023 · Education, News
Maximizing Yield and Purity: The Essential Guide to Centrifugal Partition Chromatography
Centrifugal partition chromatography (CPC) is a highly effective and efficient liquid-liquid preparative chromatographic technique that is gaining increasing popularity among scientists, researchers and laboratory technicians. This technique utilizes two immiscible liquid…
február 14, 2023 · Education, News
The Essential Guide to Understand Chromatography
Chromatography is an essential technique used in the separation of components from a mixture. To understand chromatography, you must know its basic principles and the many factors affecting the process.
február 13, 2023 · Education, News
Recovery, Throughput and Purity – The Chromatographer's Triangle
Chromatographic methods are used to separate and purify individual components of a mixture. Purifying compounds, however easily become a balancing act. Throughput, recovery and purity are 3 essential goals and qualities which chromatographers have to balance according to which…
január 18, 2023 · Education, News
Making the Right Choice: HPLC vs CPC for Your Purification Needs
Since the early days of chromatography, which can be traced back to Mikhail Tsvet's famous plant pigment separation experiment in 1901, numerous techniques have been developed to purify materials. One well-known method is high-performance liquid chromatography (HPLC), which has…
december 21, 2022 · Education, News
Separation, Isolation and Remediation – Advanced Chromatography
Separation, isolation and remediation are extremely important chromatographic goals, and we're going to examine exactly why. As far as chromatographic rules, Centrifugal Partition Chromatography (CPC) follows the traditional route. Where it differs is its utilization of…
december 7, 2022 · Education, News
Advanced Chromatography – CPC and Cell Design
In our previous series ‘An Introduction to Chromatography’ we looked at the main aspects of chromatography. We started with the fundamentals of the subject and then talked about more complex topics. Finally, as we wrap up the series, we arrived at Centrifugal Partition…
november 17, 2022 · Education, News
An Introduction to Chromatography – Liquid-Liquid Chromatography (LLC)
In ‘An Introduction to Chromatography’, we examine the essentials and main aspects of chromatography. Since it is a complex topic, we started with basics (defining chromatography itself, and learning how and where it began) Then, we worked our way up towards more complex…
október 16, 2022 · Education, News
RotaChrom attending SPICA 2022 in Lisbon
From October 11-14, the scientific team of RotaChrom will be in Lisbon at the 18th "International Symposium on Preparative and Industrial Chromatography and Allied Techniques", also known as SPICA 2022.SPICA is the most important worldwide event to find out about the latest…
szeptember 22, 2022 · Conferences, News
Investigating Green Chemistry Practices in CPC – Part III
Centrifugal partition chromatography (CPC) has been gaining popularity in the chemical purification industry for its ability to support sustainable processes and greener chemical production. In this third installment of our blog series, let’s delve into how you can coordinate…
szeptember 15, 2022 · Education, News
Visit ISC 22 and Meet top Chromatography Experts and Researchers
We are excited to announce that RotaChrom’s team will attend the 33rd International Symposium on Chromatography, also known as ISC. The event is going to take place in Budapest, Hungary from 18-22 September 2022 in the Budapest Congress Centre.The International Symposium on…
szeptember 6, 2022 · Conferences, Events, News
Investigating Green Chemistry Practices in Centrifugal Partition Chromatography (CPC) – Part 1
Despite its widespread use in the chemical industry, traditional preparative-scale liquid chromatography suffers from sustainability issues due to its high solvent consumption and solid waste from spent silica gel packing. On the other hand, solid support-free techniques like…
szeptember 1, 2022 · Education, News
An Introduction to Chromatography – The Chromatogram & Fraction Collection
In this series, we look at the main aspects of chromatography. We started with the basics and now we begin to work our way towards more complex topics, such as Centrifugal Partition Chromatography. Our goal is to make chromatography easy to understand, so that anyone can get a…
augusztus 9, 2022 · Education, News
Analytica 2022 – Recaps from the Team
Analytica has been a persistent supporter of the development of chemical analytics and bioanalytics for over 50 years at this point. According to the conference website, “Analytica is the world’s leading marketplace for products and services along the entire value chain for…
augusztus 4, 2022 · News
Analytica 2022 – Meet the RotaChrom team in Munich
From June 21-24, the RotaChrom team is attending the Analytica 2022 conference in Messe München. Meet Bob Madigan, our Chief Commercial Officer and Andras Gaspar, our Chief Product Officer and the whole team in Munich. We hope to see you there!
május 27, 2022 · Conferences, News
PREP 2022 – RotaChrom is going!
We are super excited to attend the PREP 2022 conference in Baltimore! Bob Madigan, our Chief Commercial Officer and Arpad Konczol, our Lead Scientific Officer, and others from our team will represent RotaChrom at our booth and workshop.
május 9, 2022 · Conferences, Events, News
In a recent NMR and chiroptical study related to kratom alkaloids, researchers used a RotaChrom CPC device.
Mitragynine (MTR) is a major alkaloid in Mitragyna speciosa leaf extract. It is a well-known plant commonly referred to as ‘kratom’. This plant is among the most studied botanical and natural products in recent memory, thanks to its notable biological effects. It is a partial…
április 8, 2022 · News, Studies
RotaChrom announced the launch of a strategic partnership with Red Mesa Science
In Addition to the Research Collaboration, the Facility Will Serve as a Reference Site for RotaChrom's SolutionRotaChrom's CPC machine now displayed in Red Mesa's facilityInfrastructure for a global leaderRed Mesa's ambitious goals are already taking shapeIrvine, CA – January…
január 18, 2022 · News, Studies
RotaChrom Technologies announces promotion of Andras Gaspar, Ph.D., to Chief Product Officer
Developer of World’s First Industrial Centrifugal Partition Chromatography Platform Extends Leadership Team.RotaChrom Technologies announced today the promotion of Andras Gaspar, Ph.D., to Chief Product Officer. In his new role, Andras will oversee all product development and…
február 23, 2021 · News, Promotion
RotaChrom Technologies partners with Cyclolab to increase production of COVID-19 treatment
RotaChrom announced the launch of a collaboration with Cyclolab Cyclodextrin Research and Development Laboratory Ltd. (“Cyclolab''), a cyclodextrin research, development and manufacturing company. The strategic partnership between Cyclolab and RotaChrom aims to develop a more…
február 9, 2021 · News, Studies
Centrifugal Partition Chromatography webinar
RotaChrom organizes its first webinar with the focus of Centrifugal Partition Chromatography on an industrial-scale and its applications in the cannabis industry. In the presentation Mr. Kelly Peterson, RotaChrom's North American Director of Technical Services, will give a…
december 3, 2020 · Events
Scientific publication on the industrial-scale CPC platform
A peer-reviewed scientific paper describing the concept and realization of RotaChrom’s pCPC platform has been presented in the prestigious journal Organic Process Research & Development (OPR&D) published by the American Chemical Society. The article provides detailed insight…
november 23, 2020 · Events, Studies
Virtual site visit in the RotaChrom factory
In 2020, RotaChrom's factory will also be presented in the “Night of Modern Factories” program series, an event held online this year due to the Coronavirus disease (COVID-19), allowing the public to participate in nocturnal factory tours at various manufacturers. The aim of…
november 11, 2020 · Events, Exhibitions
Keynote lecture at the ACS Fall 2020 Virtual Meeting & Expo
The regular semi-annual meeting of the American Chemical Society (ACS) was held virtually this year between 17 and 20 August with 250+ broadcast sessions and 6000+ presentations. RotaChrom’s research chemist, Dóra Rutterschmid gave a comprehensive talk on the concept and the…
november 3, 2020 · Exhibitions, News
Supporting Kratom Research and Standardization
Lead Scientific Officer at Rotachrom will talk about the R&D efforts that support the research and standardization of a special medicinal plant, called Kratom. The R&D team has been working on Kratom purification using chromatographic technology (CPC, centrifugal partition…
május 11, 2020 · Webinars
Another prosperous event in Las Vegas
In December RotaChrom attended one of the world's most prestigious cannabis conferences, MJBizCon Las Vegas. MJBizDaily’s flagship event is one of the most eminent worldwide conferences in cannabis, which aims to drive business deals and forge valuable connections with cannabis…
december 16, 2019 · Events, Exhibitions
Best Poster Award at Prep
PESTICIDE CLASSIFICATION SYSTEM IN THE ISOLATION OF CANNABIDIOL USING CENTRIFUGAL PARTITION CHROMATOGRAPHY titled poster of RotaChrom Technologies won 3rd place in the Best Poster Award (Industry section) at PREP 2019, Baltimore.PREP is the most recognized international…
július 11, 2019 · Awards, Exhibitions
Exhibiting at CPhI China
Exhibiting at CPhI & P-MEC China, RotaChrom enters Chinese pharmaceutical market.CPhI has been a well-known pharmaceutical event for 30 years bringing different stakeholders of the pharmaceutical industry together under one roof in nine event locations around the world. Each…
június 22, 2019 · Exhibitions, News
Great recognition at HPLC
RotaChrom’s unique purification technique earned a great recognition at HPLC 2019.2019 is the first year that the International Symposium on High-Performance Liquid Phase Separations and Related Techniques (HPLC) was held in Italy. The event is the most important international…
június 21, 2019 · Exhibitions, News
Berlin conference in cannabis
RotaChrom at International Cannabis Business Conference 2019, BerlinICBC is an international B2B cannabis conference series organized at numerous different locations all around the world each year by the International Conference Group. ICBC Berlin, being the first meeting point…
április 3, 2019 · Exhibitions, News
Pharma congress in Budapest
RotaChrom presence in the pharmaceutical industry became stronger by presenting at PHARM Connect Congress.In the last years the unique RotaChrom technique has become widely used in the Cannabis industry, and it also earned a strong awareness in the pharmaceutical industry. Our…
március 14, 2019 · Exhibitions, News
Presentation at FCBC London
RotaChrom presented the technology of cannabinoid isolation by Centrifugal Partition Chromatography at the Future Cannabis Strategies Conference 2019 in London.The Future Cannabis Strategies Conference series was launched in January 2019 in London by Arena International Events…
február 1, 2019 · Exhibitions, News
Great success at MJBizCon
This year’s MJBizcon Conference – the world's largest cannabis industrial exhibition – brought huge success for RotaChrom Technologies in Las Vegas. Amongst a thousand exhibitors, the company’s 40 m2 high-standard booth was one of the most visited stands in the Las Vegas…
december 7, 2018 · Exhibitions, News
RotaChrom at CPhI Worldwide
RotaChrom, one of the decisive players of the chromatographic space, exhibited at the CPhI Worldwide expo on an exclusive stand, putting its industrial scale CPC (Centrifugal Partition Chromatography) machine in the focus.CPhI Worldwide together with co-located events ICSE…
október 25, 2018 · Exhibitions, News