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Industrial Scale Centrifugal Partition Chromatography

Pharmaceuticals / Natural Extracts / Food & Beverages / Cosmetics & Fragrances More about RotaChrom Technologies

What does RotaChrom do?

RotaChrom has developed the world’s first commercially available industrial scale Centrifugal Partition Chromatographic (iCPC) technology platform. The technology has significantly revolutionized the purification industry by providing cost-effective commercial scale chromatographic solutions to Partners all over the world. RotaChrom is currently working with a broad array of industries including pharmaceutical, nutraceutical and botanical companies in the Americas, Europe, China, and India.

RotaChrom’s mission is to become industry standard and redefine the expectations for companies active in the following industries: pharmaceutical, hemp industry, herbs & cannabis, phytopharma, nutraceuticals, food & beverages, cosmetics & fragrances and more.


RotaChrom's expertise

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Natural extracts

Do you want to purify major or minor cannabinoids on an industrial scale? RotaChrom offers scalable, versatile and cost-efficient platforms to isolate and purify your target compound while eliminating illicit substances and even pesticides.

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RotaChrom‘s CPC system has almost no limits on adaptation from small molecule APIs to macromolecules or from hydrophobic lipids to completely hydrophilic peptides on the same instrument. Scaling up from grams to tons/month production can be achieved on the same platform within weeks.

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Cosmetics & Fragrances
Food & Beverages

If you use conventional chromatographic technology for isolating compounds then RotaChrom can offer you a much more efficient, cost-effective, adaptable and scalable solution for your chromatographic challenge.

RotaChrom's expertise

RotaChrom's expertise

RotaChrom’s Products & Services


Pilot-scale centrifugal partition chromatographic instrument for Research & Development and batch to batch small-scale purification purposes.


The largest serialized centrifugal partition chromatographic platform in the world, designed for industrial scale purification.


The production scale CPC system including an iCPC instrument and additional SKIDS for solvent preparation, recycling and recirculation for an automated quasi-continuous production.


At-line system, which incorporates the purification and recycling platforms, complemented with a matching target material concentration station.

Feasibility study

A study run by RotaChrom’s laboratory with the Partner’s material to evaluate the possible outcomes and to prove the successful purification of the target compound by RotaChrom CPC technology.

Method development and optimization

Tailor-made methods are being developed and adapted on RotaChrom CPC systems for the individual matrices and compounds of interest, derived from our Clients.

Optional production scale pilot study

After a feasibility study in certain cases it is a recommended option to conduct a production scale pilot study with RotaChrom’s expert team to optimize future operational parameters and enhance potential yield and profit.

Factory design consultancy

Joint efforts with Clients to find the most effective and viable layout and factory setup. RotaChrom prior installation, details installation requirements and recommends optimal layout for the individual processes of the Client, while local safety specifications and regulatory requirements are applied and defined beforehand by the Client.

Maintenance service agreement

Regular preventive maintenance to ensure safe and reliable operation.

Rotachrom Technologies LLC. | Industrial Scale Centrifugal Partition Chromatography