ROTACHROM

Delivering silica-free, liquid–liquid CPC purification solutions that simplify downstream workflows, scale from process development to industrial production, and adapt to changing capacity, purity, and regulatory requirements.

BRIDGING BULK
SEPARATION AND FINAL
POLISHING IN THE
DOWNSTREAM
PROCESSING WORKFLOW

CPC technology delivers highly selective separations making it well suited for complex compounds with similar physical and chemical properties across pharma, biotech, botanicals, and nutraceuticals. It fits naturally into downstream processing workflows, bridging the gap between bulk extraction and high-purity isolation where extraction alone is no longer sufficient to meet purity or regulatory requirements.

From APIs and bioproducts to natural bioactives and functional ingredients, CPC ensures high yield, reproducibility, and gentle handling of sensitive molecules.

SCALABLE PURIFICATION BUILT
TO GROW WITH YOUR
PROCESS FROM R&D
TO CONTINUOUS AND FULL
INDUSTRIAL PRODUCTION

RotaChrom’s CPC technology is built for true scalability, preserving the same separation principles from benchtop development through pilot-scale to full industrial production. The same methodology, solvent systems, and process logic can be transferred without re-engineering, minimizing scale-up risk and validation effort.

Beyond scale-up, productivity can be increased through scale-out by operating multiple CPC units in parallel or in continuous-loop configurations for nonstop manufacturing. This modular scalability allows manufacturers to grow capacity stepwise, align investment with demand, and maintain process continuity from R&D to high-throughput industrial production.

Technology

TOTAL PROCESS CONFIDENCE ALIGNING
CUTTING-EDGE SYSTEMS WITH
STRATEGIC INSIGHT

Built on the principles of liquid-liquid separation and CPC, our portfolio spans from benchtop through pilot, continuous to industrial-scale CPC systems, complemented by digital method development tools, solvent handling platforms, and automation solutions.

This integrated portfolio enables customers to develop, validate, and industrialize purification processes within a single technological framework — reducing development timelines, scale-up risks, and long-term operating costs.

Products

EXPERT-LED SERVICES
TO DE-RISK AND
ACCELERATE YOUR
PURIFICATION PATH

Beyond hardware, we provide comprehensive method development, feasibility studies, and technical transfer support to ensure that purification workflows are executed seamlessly while minimizing scale-up risks, validation efforts, and operational disruption. Our service portfolio is designed to de-risk your purification journey through expert-led collaboration and cutting-edge digital tools.

Whether validating a new compound or outsourcing complex chromatography, our team of liquid-liquid separation specialists provides the data-driven insights and scalable strategies needed to accelerate your path to market.

Services