products

CPC Modeler

Digitally Powered benchtop-sized Method Development in Chromatography

CPC Modeler benchtop system

The CPC Modeler is a benchtop-sized CPC platform, designed to accelerate method development during the research phase and streamline your transition to production-scale purification. It integrates an intuitive digital toolkit, the CPC Simulator, to model purification strategies, and validate them on a Benchtop CPC system, ensuring operational efficiency. The platform also enables seamless scalability to production-level purification without re-engineering across your downstream workflow.

Accelerate Method Development with a benchtop device and in In-Silico Simulation for R&D

Scale-UP made Simple from Milligrams to Manufacturing Without Changing Your Method

Built for Compliance and Industry Standards

Parameter Specification
Technology Liquid–Liquid Chromatography (LLC), Centrifugal Partition Chromatography (CPC)
Primary Purpose Benchtop LLC platform for method development and entry-level system for production scale-up
Rotor Volume 250 mL
Flow Rate 1–50 mL/min
Throughput Milligrams to gram pe cycle
GMP Compliance Pharma GMP Compliant Device (Eudralex Volume 4.)
Additional Software Tool included In Silico CPC Simulator Tool

GMP-rCPC

Pilot-Scale Liquid–Liquid Chromatography and Scalable Purification

GMP-rCPC pilot-scale CPC platform

The GMP-rCPC is a pilot-scale CPC platform. It bridges the gap between method development and commercial production by offering the flexibility and throughput to support both small-batch, campaign-style research and continuous manufacturing workflows. The system with the solvent handling modules as turn-key add-ons is fully customizable for isolation, separation, purification, and remediation tasks. The platform also enables seamless scalability without re-engineering across your downstream workflow.

High Throughput, Outstanding Purity and Yield

Flexible Scale-Up and Scale-Out Without Re-Engineering

Built for Regulatory Compliance and Industry Standards

Parameter
Specification
Technology
Liquid–Liquid Chromatography (LLC), Centrifugal Partition Chromatography (CPC)
Primary Purpose
Pilot-scale GMP purification and method validation; scale-up-ready at-line use
Rotor Volume
2.2 L pilot-scale rotor
Flow Rate
100–300 mL/min
Throughput
Grams to hundred grams per cycle
Operation Modes
Ascending and descending
GMP Compliance
Pharma GMP Compliant Device (Eudralex Volume 4.)

Continuous CPC

True Continuous Manufacturing with Dual-Rotor Centrifugal Partition Chromatography

Continuous CPC system

The Continuous CPC is designed for uninterrupted, high-throughput purification. Built on two interconnected GMP-rCPC units operating in dual-rotor configuration, it enables continuous compound injection, seamless fraction collection, and continuous manufacturing. This setup drastically boosts productivity compared to batch-mode systems, while also reducing downtime, lowering solvent and energy consumption, minimizing manual intervention, and increasing overall process efficiency.

Unmatched Productivity in a Compact Footprint

Smart Solvent Handling and Modular Design

Built for R&D and Industrial Use

Parameter Specification
Technology Liquid–Liquid Chromatography (LLC), Continuous Centrifugal Partition Chromatography (Continuous CPC)
Primary Purpose Continuous purification for pharmaceutical, biotech, and fine chemical production
Configuration Dual-mode, dual-rotor, 2× GMP-rCPC units with synchronized control
Operation Mode MDM / Trapping MDM / Continuous injection
Rotor Volume 4.4 L
Flow Rate 500 mL/min
Sample Injection Continuous injection of sample (300 mL/min)
Throughput Hundred grams to kilogram per cycle
Compliance Pharma GMP compliant (Eudralex Volume 4.), ATEX Zone 2 compliant design

iCPC with solvent preparation and recycling system

Production-Scale Chromatography Platform with Integrated Solvent Management

The iCPC with solvent preparation and recycling system is an industrial-scale purification platform that combines the iCPC, the largest commercially available CPC system, with a fully automated solvent preparation, recovery, and regeneration system, forming a complete and turnkey production platform. The system is controlled via a PLC, which ensures precise parameter tuning, allows for integration with multiple devices, and supports real-time process automation.

Industrial-scale Throughput, Outstanding Purity and Yield

Flexible Multi-Skid Integration for Tailored Industrial Production

Seamless Scale-Up for Industrial Purification

Parameter
Specification
Technology
Liquid–Liquid Chromatography (LLC), Continuous Centrifugal Partition Chromatography (Continuous CPC)
Primary Purpose
Fully integrated platform for cost-effective, large-scale purification
Configuration
iCPC unit + integrated solvent handling (prep, recovery, regeneration)
Rotor Volume
23 L
Flow Rate
800–5000 mL/min
Throughput
Kilograms per cycle
Solvent System
Integrated solvent and sample handling system
Compliance
Pharma GMP compliant (Eudralex Volume 4.) design; ATEX Zone 2/C1D2 compliant design