CPC Chromatography: A Versatile Solution for Analytical and Preparative Scale Purifications

CPC Chromatography proves highly effective in addressing chromatographic challenges, offering versatile applications on both analytical and preparative scales. The distinct objectives of each scale highlight the adaptability of CPC in overcoming challenges associated with large-scale purifications.

Analytical Scale Separations:

• Objective: Comprehensive understanding of the sample’s composition and characteristics.
• Parameters: High resolution, peak capacity, speed, and selectivity.
• Insights: Researchers gain detailed knowledge about the sample’s components.
• Objective: Generate significant quantities of purified materials, eliminate impurities, and maximize the yield of the Compound of Interest (CoI).
• Additional Parameters: Scalability, yield, throughput, and productivity.
• Application Areas: Pharmaceuticals, nutraceuticals, botanical extracts, requiring substantial amounts of purified materials.

Leveraging CPC for Preparative Scale Purification

• CPC Advantages: Scalability, high yield, and productivity make it ideal for large-scale applications.
• Industries: Pharmaceuticals, nutraceuticals, botanical extracts, benefiting from CPC’s ability to handle large sample volumes and produce high-purity compounds.

CPC Chromatography Advantages over HPLC

• HPLC Challenges: High operating and waste management expenses, particularly with silica as the solid stationary phase.
• CPC Advantages: Liquid-liquid chromatography eliminates the need for silica, providing precision molecular separation without associated complications or costs.
• RotaChrom’s CPC Solution: Output capacity of approximately 20 kg/day, no sample loss due to irreversible absorption, and an individual cell design for efficient, seamless operation.

RotaChrom’s CPC Technology

• Output Capacity: Remarkable 20 kg/day ensures high productivity for large-scale purification needs.
• Advantages over HPLC: No sample loss due to irreversible absorption, individual cell design streamlining the purification process.
• Cost-Effectiveness: Low maintenance requirements and the ability to reuse solvent systems contribute to sustainability and cost-effectiveness.

In conclusion, CPC Chromatography, especially through RotaChrom’s innovative technology, stands as a promising alternative for preparative purification needs. Its scalability, high yield, and cost-effectiveness make it an attractive choice for various industries, offering a powerful solution for large-scale purification requirements.