RotaChrom CPC
Instruments & Solutions

RotaChrom offers different CPC technology platforms:
the rCPC, iCPC and the pCPC

RotaChrom rCPC platform


RotaChrom’s rCPC device is a pilot-scale centrifugal partition chromatographic (CPC) instrument which is ideal for pilot-scale purification as well as method optimization prior to manufacturing on industrial-scale. With this platform, manufacturers have no limit to system adaptation for any purification challenges from small molecule APIs (active pharmaceutical ingredients) to macromolecules or from hydrophobic lipids to hydrophilic peptides all on the same machine.

iCPC instrument


The iCPC is currently the largest, commercially available centrifugal partition chromatographic instrument in the world. RotaChrom is the sole manufacturer and distributor of the industrial scale CPC instrument and provides various products and services facilitating silica-gel-free preparative industrial scale purification. Buying an iCPC device provides many technical and economical advantages to your current and future purification tasks. The iCPC is only available as a stand-alone version for special set-ups.

pCPC instrument - product picture


The pCPC unit is comprised of the RotaChrom iCPC instrument and a SKID system which automates the purification process, from solvent preparation to recycling under ex-proof environment. RotaChrom’s pCPC platform offers high throughput, outstanding purity, increased yield and cost efficiency compared to current alternative purification platforms.

pCPC+ COI - product picture


This setup is comprised of the RotaChrom pCPC system, as well as the target compound handling system. The additional compound of interest (COI) platform enables to concentrate and refinish the target compounds. This hyphenated platform is adaptable for the individual Client requirements and throughput.

RotaChrom CPC Device Overview

  • Technical features ¹rCPCiCPC
  • Loading capacityup to 150 g/cycleup to 1500 g/cycle
  • Average flow rate~250 mL/min~2500 mL/min
  • Throughput ²2 kg/day20 kg/day
  • Weight470 kg / 1036 lbs1600 kg / 3527 lbs
  • Dimensions ³

    3'3” x 4'3” x 3'5”4'11” x 5'11” x 4'9”

¹ Industry relevant certifications (i.e. ATEX, UL, CSA) are available upon request for pCPC platform and subjected to individual design reviews, based on the operational environment.

² Amount of the crude/input material and based on 2 shifts (16h)/day operation scheme.

³ Total footprint of the complete system, including SKID platforms,  may vary due to the individual Client location. For further details please refer to FAQ and contact RotaChrom directly.

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