Pharmaceuticals / Natural Extracts / Food & Beverages / Cosmetics & Fragrances
RotaChrom has developed the world’s first commercially available industrial scale Centrifugal Partition Chromatographic (CPC) technology platform. The technology has significantly revolutionized the purification industry by providing cost-effective commercial scale chromatographic solutions to Partners all over the world. RotaChrom is currently working with a broad array of industries including pharmaceutical, nutraceutical, health and beauty, and botanical companies, research and academia, and more in the Americas, Europe, China, India, and Asia.
Scale up your purification process and production from mg to 20kg/day
Versatile purification systems to work with a wide range of COIs
Select between lab-scale, pilot-scale, or industrial-scale purification
Do you want to purify major or minor cannabinoids on an industrial scale? RotaChrom offers scalable, versatile and cost-efficient platforms to isolate and purify your target compound while eliminating illicit substances and even pesticides.
RotaChrom‘s CPC system has almost no limits on adaptation from small molecule APIs to macromolecules or from hydrophobic lipids to completely hydrophilic peptides on the same instrument. Scaling up from grams to tons/month production can be achieved on the same platform within weeks.
If you use conventional chromatographic technology for isolating compounds then RotaChrom can offer you a much more efficient, cost-effective, adaptable and scalable solution for your chromatographic challenge.
Use CPC for isolation, separation, and remediation
High production potential
No more expensive silica gel or resign are needed, CPC only uses liquids for separation.
CPC generates significantly less hazardous waste compared to traditional chromatography, since 95% of the solvents can be recycled and recirculated into the system.
The CPC infrastructure can be adapted for a new purification project within hours.
Chromatography is a process for separating components of crude mixtures. A target compound may have ingredients that are useful, beneficial and are highly valuable for commercially sold products, while others must be extracted through a thorough and careful purification process.
Centrifugal partition chromatography (CPC) is a cost-efficient preparative liquid-liquid chromatographic technique with unique features, such as robustness and versatility. It is particularly suited for the large-scale fractionation and purification of crude natural products. It is utilized in the pharmaceutical industry for the analysis and purification of drugs, and botanical industry for purification of botanical oils, however, it is also highly involved in the downstream processing of foods, beverages, fragrances and fine chemicals.
The rCPC platform is designed to execute pilot scale purification tasks within a laboratory environment, making it ideal for any batch, smaller or larger, or campaign type of research work as well as continuous batch production. Test your product before rolling them out to the market.
The iCPC is the largest serialized centrifugal partition chromatographic platform in the world, designed for industrial-scale purification projects in continuous batch operation mode, with the capacity to process hundreds of kilograms per month of crude input material. Bid farewell to silica, and make 20+kg end product each day more with flexible, affordable, robust, future-proof chromatography.
This tailor-made system pCPC by RotaChrom is a combination of iCPC and solvent preparation and recovery, and regeneration. It also delivers a proprietary automated biphasic solvent system preparation platform, providing a flexible and continuous feed to our iCPC instrument. Automate your complete purification process and make products that meet all standards.
pCPC combined with the Heivap platform is a complex solution: this fully integrated production system enables complete solvent handling solution besides the iCPC purification platform. Adapt it to your very needs to ensure you concentrate and refinish your target compounds without having to compromise.
A study run by RotaChrom’s laboratory with the Partner’s material to evaluate the possible outcomes and to prove the successful purification of the target compound by RotaChrom CPC technology.
Tailor-made methods are being developed and adapted on RotaChrom CPC systems for the individual matrices and compounds of interest, derived from our Clients.
After a feasibility study in certain cases it is a recommended option to conduct a production scale pilot study with RotaChrom’s expert team to optimize future operational parameters and enhance potential yield and profit.
Joint efforts with Clients to find the most effective and viable layout and factory setup. RotaChrom prior installation, details installation requirements and recommends optimal layout for the individual processes of the Client, while local safety specifications and regulatory requirements are applied and defined beforehand by the Client.
Regular preventive maintenance to ensure safe and reliable operation.
RotaChrom Technologies LLC (Headquarters)
7 Szabadság Square, Budapest, HU-1054
+36 70 885 6922
RotaChrom North America Inc.
300 Spectrum Center Drive, Irvine, CA 92618
+1 843 781 9210