A major benefit of the iCPC platform is its Adaptability. Traditional LC has limited adaption for different applications and sometimes requires a complete change in instrument or brand new column to be installed. The iCPC system has almost no limits on adaptation: from small molecules to macromolecules or from extremely hydrophobic lipids to completely hydrophilic peptides.
On a single instrument you can purify as many types of compounds as you would like while complying with IQ, OQ, PQ, Cleaning validation and cGMP. The only limiting factor is the manufacturer’s capacity.
Direct Scale up
Scale up is another major advantage of the iCPC system. With conventional LC techniques, scale up often requires a complete system redesign which could take years, iCPC scale up is much simpler from few gram batches to tons/month production. You simply increase the loading capacity by utilizing the larger cell sizes. RotaChrom offers 3 prep CPC extraction cell sizes.
With iCPC, scale up is a cost-effective and flexible process: